Lead inventor: Michael Pluth
Co-inventors: Matt Cerda, Michael Pluth, Yu Zhao
Licensing contact: Christine Gramer
1. Technology Overview
The invention focuses on thiol-triggered sulfenyl thiocarbonates and sulfenyl thiocarbamates that release carbonyl sulfide (COS) and hydrogen sulfide (H2S) in the presence of biologically relevant thiols. These compounds offer a concomitant fluorescence response, providing optical indication of COS and H2S release. The technology is currently in the development stage, with promising cross-industry applications in biological detection, imaging, and targeted drug delivery.
2. Key Features and Benefits
- Fluorescence response: Provides optical indication of COS/H2S release.
- Diversifiable releasing group: Enables conjugation to various fluorophores and drug molecules.
- Versatility: Applicable to various industries, including biotechnology and pharmaceuticals.
- Scalability: Synthesis processes can be scaled for larger quantities.
- Targeted applications: Ideal for biological detection, imaging, and drug delivery systems.
3. Applications and Market Focus
- Biological detection: Use in detecting and imaging biological processes involving COS/H2S.
- Drug delivery: Integration into targeted drug delivery systems.
- Biotechnology: Development of novel biological detection and imaging methods.
- Pharmaceutical industry: Synthesis of complex organic molecules for various applications.
- Chemical industry: Use in advanced synthesis techniques and equipment.
4. Commercial Advantages
- Strategic benefits: Provides reliable and scalable COS/H2S releasing compounds for various applications.
- Implementation advantages: Facilitates integration into existing biological detection and imaging systems.
- Market positioning: Positions technology as a key enabler for advanced biological detection and drug delivery systems.
- Competitive advantages: Offers fluorescence response and diversifiable releasing group compared to existing methods.
5. Partnership Opportunities
- Ideal licensing partners: Biotechnology firms, pharmaceutical companies, chemical industry leaders.
- Cross-sector partnership benefits: Collaboration opportunities across biotechnology and pharmaceutical industries.
- Diverse market opportunities: Potential for global market expansion in regions with strong biotechnology and pharmaceutical industries.
- Collaborative development: Opportunities for joint development of hybrid devices and custom synthesis services.
Patent filing: US20210214368A1